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KMID : 1132720130110030155
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Genomics & Informatics
2013 Volume.11 No. 3 p.155 ~ p.160
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Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server
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Jung Sung-Hoon
Bae Se-Eun
Ahn In-Sung
Son Hyeon-S.
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Abstract
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Structural information has been a major concern for biological and pharmaceutical studies for its intimate relationship to the function of a protein. Three-dimensional representation of the positions of protein atoms is utilized among many structural information repositories that have been published. The reliability of the torsional system, which represents the native processes of structural change in the structural analysis, was partially proven with previous structural alignment studies. Here, a web server providing structural information and analysis based on the backbone torsional representation of a protein structure is newly introduced. The web server offers functions of secondary structure database search, secondary structure calculation, and pair-wise protein structure comparison, based on a backbone torsion angle representation system. Application of the implementation in pair-wise structural alignment showed highly accurate results. The information derived from this web server might be further utilized in the field of ab initio protein structure modeling or protein homology-related analyses.
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KEYWORD
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backbone torsion angle, protein database, secondary protein structure, structure alignment
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